C. Rescinnamine
Synonyms Reserpinine; Anaprel; Apoterin S; Cartric; Cinnaloid; Moderil;
Biological Sources It is obtained from the roots of Rauvolfia serpentina (L.) Benth. (Apocynaceae)
(Rauvolfia, Chandra, Sarpaganda).
Chemical Structure
3, 4 5-Trimethoxy-cinnamic acid ester of methyl reserpate; (C35H42N2O9).
Isolation Rescinnamine may be isolated from step (5) onwards as described under Morphine.
Characteristic Features
1. It is obtained as fine needles from benzene having mp 238-239°C (under vacuum).
2. Its specific optical rotation is [α]24D - 97° (C = 1 in chloroform).
3. It has uvmax (methanol): 228, 302 nm (log ε 4.79, 4.48).
4. Solubility Profile: It is moderately soluble in methanol, benzene, chloroform and other organic solvents; and practically insoluble in water.
Uses It is mostly used as an antihypertensive.
