Mei Hu, Kazunori Ogawa, Yutaka Sashida Xiao Pei-Gen (1995), Triterpenoid glucuronide saponins from root bark of aralia armata, Phytochemistry, Volume 39, Issue 1, P.179-184
Abstract
Seventeen oleanane-type saponins were isolated from the root bark of Aralia armata. Their structures were elucidated by chemical and spectral evidence. Except for oleanolic acid 28-O-β-D-glucopyranoside all the saponins have a glucuronopyranosyl residue at the C-3 position of the aglycones and other sugar substitutes bind to glucuronic acid at positions C-3 and/or C-4. A comparison of saponin constituents of this plant with other araliaceous plants is provided.
Keywords
Aralia armata; Araliaceae; root bark; triterpenoid saponin; oleanolic acid glucuronide
INTRODUCTION
It is known that the roots of several members of Aralia species have been used as folk medicines for rheumatism, tonic and diabetes in China, Japan and Russia. In the early part of the sixties, Kochetkov et al. [1] isolated physiologically active saponins, aralosides A, B and C, first from this genus. Many triterpenoid saponins
have recently been isolated from several Aralia species [2-9]. A. armata (Wall.) Seem. is one of common herbal medicines of the genus Aralia in China. No chemical work, however, has been done on this plant. The present paper deals with the isolation and structure determination of16 oleanolic acid-based saponins along with a minor saponin of hederagenin from the root bark of this plant.
